Thoughts on Twitter's API - Twython and Tweepy
All things are great with Twython. But its a pity as Twython doesn't support Twitter's Streaming APIs at this point of time. So if you want to make use of Twitter's Streaming API, you might want to check out Tweepy.
But after testing Tweepy, I noticed that Tweepy's OAuth Handler thing is not working.
Therefore, to use Twitter's Streaming API, you can use Twyton for OAuth authencation and than using the token and key in Tweepy.
This will help you get the best of both worlds.
Store the token and key (using Twython's OAuth methods ) into your database, and than reuse them in Tweepy's Streaming API.